Se non l'hai già fatto, corri a leggerti la fenomenale intervista a Doc Searls su Creative Commons:

"...This was the problem with all these dot-com acronyms with a 2 in the middle -- B2B, B2C and so on. "To" was the wrong preposition. As Christine Boehlke put it to me once, the correct middle letter should have been W, because in a real marketplace we do business with people not to them. Does anybody ever shake hands and say "Nice doing business to you!"? Because the Net is more fundamentally a place than a pipe, we do business with each other there, not just to each other. Critical difference..."

Grande Doc.